Lecture notes CM3024, Dr. M. Pravda, 2013 - 2014 |

ANALYTICAL CHEMISTRY - COMMON
TOPICS

**
Lecture 1** -
Introduction to analytical chemistry, Aim and scope of analytical chemistry,
Analytical procedure, Sampling methods, Classification of analytical methods.

**Lecture 2**
- Sample preparation methods - Dilution, Preconcentration, Decomposition,
Derivatisation.

**
Lecture 3** -
Tools of the trade

**Lectures
4-5** - Wet methods of Analysis - Gravimetry, Thermogravimetric Analysis (TGA), Volumetric methods, Acid-base titrations, pH of
aqueous solutions of weak acids and bases, Titration curves, Acid-base
indicators, pH at the equivalence, Buffers, Titration of polyprotic acids,
Primary Standards in acidimetry and alkalimetry, Fractional Composition
Diagrams, Complexometric titrations with EDTA.

**
Lecture 6** - Redox titrations.

**
ANALYTICAL
ELECTROCHEMISTRY - INTRODUCTION**

**Lecture
7** - Introduction to electrochemistry, charge, potential, current,
conductivity, mobility, resistance, electrochemical cells, EMF, anode, cathode,
Gibbs free energy and EMF, the Nernst equation, equilibrium constant, standard
reduction potential, Potentiometry, Reference electrodes, membrane electrodes,
glass pH electrode, direct potentiometry, potentiometric titration

**
Lecture 8** - Conductometry, molar conductivity, weak and strong
electrolytes, direct conductometry, conductometric titrations, introduction to
voltammetric methods and electrochemical reactions

**DATA
ANALYSIS - CHEMOMETRICS**

**
Lectures 9-10** - Basic statistics, Univariate methods, data, errors, probability
distributions, mean, standard deviation, variance, relative standard deviation,
standard error of measurement, confidence intervals, order statistics, median,
quartiles, boundaries, box graph, outliers, skewness, curtosis, uncertainty
propagation.

**
Lecture
11** - Calibration, Bivariate data, Linear Regression, slope, intercept,
Non-Linear Regression, least squares method, analysis of residuals, regression
model, heteroscedasticity, correlation coefficient, coefficient of
determination, iteration, convergence

**
Lecture
12** - Statistical testing

**RECOMMENDED READING**

**
Table
of pKa values of common acids and bases**

**
List of
common pH indicators ***- structure, transition point, colour change*

**
List of
common redox indicators** - *structure, transition point, colour change*

Disclaimer: The content of this site is designated for the registered UCC students only. No compatibility problems should occur. Requires the use of the freely available software only.

updated by M. Pravda 15 Nov 2013 |